Hello, I found that when using library(MetaboAnalystR), the download of files under the path https://www.metaboanalyst.ca/resources/ will fail. For example, “https://www.metaboanalyst.ca/resources/libs/kegg/metpa/mmu.qs” and “https://www.metaboanalyst.ca/ resources/libs/compound_db.qs”; and when I try to download it directly on the web page, I don’t get the correct qs file because it can’t be opened with qs:qread. Please pay attention to the content updated after April 30, 2026, to see if there is any wrong operation under this path that makes the files unavailable. Thank you very much to MetaboAnalystR and your team, I have benefited a lot.
The URL should be: https://www.metaboanalyst.ca/MetaboAnalyst/resources/libs/kegg/metpa/mmu.qs. The issue is related to our recent update to address the issue with the “qs” R package - which was removed in the recent R release
Thank you for your reply, but I still found the same problem. The files downloaded from the two links “https://www.metaboanalyst.ca/resources/libs/kegg/metpa/mmu.qs” and "https://www.metaboanalyst.ca/MetaboAnalyst/resources/libs/kegg/metpa/mmu.q"s" are consistent. I still get an error when I execute the following code:
________________________________________________________________________
library(MetaboAnalystR)
Bioconductor version 3.12 (BiocManager 1.30.12), ?BiocManager::install for help
Bioconductor version ‘3.12’ is out-of-date; the current release version ‘3.23’
is available with R version ‘4.6’; see Bioconductor - Install
MetaboAnalystR 3.1.0 initialized Successfully
qs::qread(“/home/Metabolome/test_lxj/fankui/test/mmu.qs”)
Error in qs::qread(“/home/Metabolome/test_lxj/fankui/test/mmu.qs”) :
QS format not detected
_________________________________________________________________________
The files downloaded before April 30, 2026, can be opened normally, so I was wondering if the update process did not consider users who still use qs. Can the files be read using qs2? I haven’t tried it yet because I haven’t successfully installed qs2 yet.
This should be the cause - MetaboAnalyst web is updated, MetaboAnalystR is not (there are 3 weeks delay)
Solution:
Use the web for now, or try to fix qs2 installation.