How to proceed DIA with mxML which was converted from Waters' MSe?

MetaboAnalyst
,
1

I was using mxML files from water to process the LC-MS analysis.
It was converted from MSe by Waters. Everything went well until the identification.
Since it was converted from MSe, they could not provide a SWAITH-file.
Is there any substitution for the SWATH-file, or any method to customized a SWATH-files which can fit MSe?

Thanks!

2

Hello,
I am doing the same as well… did you already find a solution ?

Thanks !

3

Not yet. We are still working on it.

But for a way to bypass, I assume you are also using Progenesis from Waters, you can generate an identification result table and then import it into MetaboAnalysis R.
There is also a progensis plug-in which can export the MS/MS data, but we are still working on it as well.

Good luck!

4

Thank you very much!