How to account for covariates in quantitative enrichment analysis (QEA)?

Hello, I am new to metabolomics analysis. Is MetaboAnalyst able to account for covariates when performing QEA? Either explicitly, e.g. by allowing labels in addition to group when submitting raw data, or implicitly, e.g., by taking ranks/stats as input, similar to GSEA?

Not currently. You can do statistical analysis with covariate adjustment. The results can then be used for ORA (targeted metabolomics) or GESA/Mummichog (untargeted metabolomics)

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