Hello all, I am using a GSEA approach to run pathway analysis on my metabolomics data. this analysis produces the plot that reminds me a volcano plot with pathways arranged according to their p-value on the y-axis and NES on the x-axis. On this plot NES (i.e. enrichment scores) can be negative or positive. How is this determined? How should I interpret this plot?
ZA17_DH_GESA.pdf (111.2 KB)