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Single node: by default, users can use mouse to drag a single node - simply hold down left click button and drag-drop the node to a new position.
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Node-neighbours: set the Scope submenu to select the option Node-neighbours. Drag and drop one of the highlighted genes to the new position.
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Highlighted nodes: make sure to highlight the group of nodes that are to be moved (please refer to this post). Set the Scope menu to Highlighted nodes. Drag-and-drop one of the highlighted genes to the new position.