Enrichment analysis - data

MetaboAnalyst
1

Hello,

For enrichment analysis, can we use peak intensity data or is it supposed to be used only with metabolite concentrations?

Thank you!

2

I assum you refer to the [Enrichment Analysis] for targeted metabolomics

  • Single Sample Profiling (SSP) requires concentrations in order to compare with literature values.
  • ORA or QEA can be concentration or any relative concentration measures (i.e. peak intensitieis) as there is no quantitative comparion with public data involved