Yes, you can delete nodes (and their associated edges) from the current network.
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First you need to select the nodes using checkbox from the Node Table in the left pane.
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Then click the Delete button at the top of the node table. A confirmation dialog will appear asking if you really want to delete these nodes.
Note, this action will trigger network re-arrangement, especially if hub nodes are removed. In addition, “orphan” nodes may be produced due to removal. These nodes will also be excluded during re-arrangement.