Which datasets are appropriate for meta-analysis?

Here are some basic considerations or recommendations for data collection for meta-analysis

  1. All datasets should have been collected under comparable experimental conditions, and/or have similar hypothesis or mechanistic underpinnings;
  2. Only two-group comparisons are supported at the moment (i.e. control vs. treatment);
  3. All datasets must have (or can be converted to have) same gene ID type, with the majority of them overlap;
  4. It is best to keep all data on the same scale or range (i.e. both raw or normalized in the same way).