No Global Proteome File uploading option for phosphoproteome data from DIA-NN

ProteoAnalyst
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1

Hi ProteoAnalyst team,

Thank you for developing such a handy tool for phosphoproteome data analysis! I would like to correct the phosphosite abundances for changes in total protein abundance for DIA-NN data. Unfortunately, ProteoAnalyst only provides this protein-abundance correction option for MaxQuant data. Could you suggest how can I do protein abundance normalization for DIA-NN data? Thanks a lot!

Best,

Chaokun

2

Hi Chaokun,

Thank you for your kind words! I have enabled support of global proteomics for DIA-NN, please give it a try and if it doesn’t work please share the dataset with me.

Best,
Guangyan