How to do the Network Analysis with 6 genes

[jamila_iqbal]

Hi,

I am working on DNA methylation meta analysis and have got 6 genes which are differentially methylated. From literature, I know 4 of these genes are involved in brain function. I want to show the biological context of these and therefore doing the NetworkAnalysis. I used Generic PPI, STRING (I checked the Require experimental validation option), cutoff 900, second order network. Doing this, I get 555 nodes, 1500 edges and 43 seeds. I have done the enrichment (KEGG, Reactome, GO:BP) on this expanded network. How can I highlight my 6 proteins in this network and if this is the right approach. Please guide, I am very new to enrichment and this forum. Thanks

[jeff.xia]

Your input genes/proteins are called “seed nodes”. There is an icon for highlighting seeds (see below). Note, you can set the highlight color (here shows white) before clicking the icon