How is functional enrichment analysis performed in mGWAS-Explorer?

Enrichment analysis aims to test of any functional modules (SNP sets, gene sets or metabolite sets) from the user-selected library are significantly enriched among those SNPs/genes/metabolites of interest in user uploaded data or current selection.

mGWAS-Explorer offers over-representation analysis (ORA) based on the hypergeometric tests to compute the enrichment p values.