Data Table Terms

[Andie]

Hi,

I have questions about the interpretation of the terms on the data table.

1. For “Dimensionality Reduction” analysis:

Feature	Stat	P-raw	P-adj
Bacteria; Firmicutes; Negativicutes; Veillonellales-Selenomonadales; Veillonellaceae; Dialister;Not_Assigned	-1.399	0.0155	0.529

What does “Stat” mean? Expression values/Fold changes? Correlation values? How were they calculated? Does a negative value represent a negative correlation?

2. For “Correlation Network” analysis:

Node	Id	Label	Degree	Betweenness	Expression
	7532	YWHAG	37	111.47	-0.393399081

What do “Degree”, and “Expression” represent? How were they calculated? Do negative values indicate a negative correlation?

Thank you very much for your help!

[Guangyan]

Hello Andie,

1. “Stat” refers to expression value identified using limma method from “Sig. Features” page. Negative refes to down regulation of the expression value in comparison to the reference group selected on “Sig Features” page.
2. Degree means the number of connections that this node contains
3. Betweenness refers to how often a node is passed in shortest paths between pairs of other nodes in the network. The higher the value, the more the node is critical in connecting other nodes.
4. “Expression” is the same as the “Stat”. It doesn’t indicate correlation. For correlation, click edge of interest on the network and you can see the actual correlation value on the bottom left corner (“Current Selection” panel)

Guangyan