Can I compare metabolic pathways between two microbes?

Yes.

  1. Start from a microbe of interest (i.e. Faecalibacterium prausnitzii)
  2. On any Pathway visualization page, click the “Compare Microbes” button in the top-right corner.
  3. Add a second taxon via the search box, assign distinct colors, and click OK.
  4. The overlay highlights which reactions are unique to each species and which are shared, making cross-feeding or competitive relationships visually apparent. The “Seed” toggle further shows overlap in required (seed) metabolites.

A screenshot example is shown below comparing F. prausnitzii and B. fragilis in Butanoate metabolism: